HLA-DPB1 gene

Gene • C1333900

Definition

This gene plays a critical regulatory role in antigen presentation and peptide binding specificity.

Synonyms

HLA-DPB1 gene • HLA-DPB1 • MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS II, DP BETA-1 • major histocompatibility complex, class II, DP beta 1 • HLA-DP HISTOCOMPATIBILITY TYPE, BETA-1 SUBUNIT • Major Histocompatibility Complex, Class II, DP Beta 1 Gene • human histocompatibility complex derived antigens-DPB1

Linked items?Related concepts, ordered by their global importance in the network.

integral to membrane    Cell membrane    Calcium Valproate    tert-Butylhydroperoxide    Endoplasmic Reticulum    Golgi Apparatus    Endoplasmic reticulum, membrane    Amiodarone    Immune response    Endosomes    Dexamethasone    cytokine-mediated signaling pathway    KEGG:hsa04145    Cell adhesion molecules (CAMs) - Homo sapiens (human)    KEGG:hsa05145    Systemic lupus erythematosus - Homo sapiens (human)    Wall of endosome    Wall of lysosome    Asthma    Antigen processing and presentation - Homo sapiens (human)   

Related concepts

# Concept name Type Relation Support Score
1 Beryllium Compound Known Explain 1.12600
2 Hepatitis B, Chronic Disease Known Explain 1.11330
3 Berylliosis Other Known Explain 1.06162
4 Myasthenia Gravis Disease Known Explain 0.99357
5 HLA-DPA1 gene Gene Known Explain 0.93378
6 Sarcoidosis Disease Known Explain 0.92336
7 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Function Known Explain 0.90010
8 MHC class II protein complex Component Known Explain 0.78697
9 Endometriosis, site unspecified Disease Known Explain 0.67784
10 Celiac Disease Disease Known Explain 0.57924
11 Asthma - Homo sapiens (human) Pathway Known Explain 0.56053
12 Allograft rejection - Homo sapiens (human) Pathway Known Explain 0.53877
13 beryllium sulfate Compound Known Explain 0.49094
14 Graft-versus-host disease - Homo sapiens (human) Pathway Known Explain 0.48508
15 Type I diabetes mellitus - Homo sapiens (human) Pathway Known Explain 0.47806
16 KEGG:hsa04672 Pathway Known Explain 0.42253
17 Autoimmune thyroid disease - Homo sapiens (human) Pathway Known Explain 0.40454
18 Multiple Sclerosis Disease Known Explain 0.36910
19 KEGG:hsa05150 Pathway Known Explain 0.36322
20 interferon-gamma-mediated signaling pathway Function Known Explain 0.34526
21 T cell costimulation Function Known Explain 0.32427
22 hydroxyhydroquinone Compound Known Explain 0.32176
23 Antigen processing and presentation - Homo sapiens (human) Pathway Known Explain 0.32148
24 KEGG:hsa05140 Pathway Known Explain 0.31077
25 KEGG:hsa05416 Pathway Known Explain 0.30804
26 T Cell Receptor Signaling Pathway Function Known Explain 0.29633
27 CD74 gene Gene Known Explain 0.22670
28 KEGG:hsa05145 Pathway Known Explain 0.19385
29 Cell adhesion molecules (CAMs) - Homo sapiens (human) Pathway Known Explain 0.18996
30 Rheumatoid Arthritis Disease Known Explain 0.17346
31 Wall of lysosome Component Known Explain 0.16873
32 Systemic lupus erythematosus - Homo sapiens (human) Pathway Known Explain 0.16298
33 KEGG:hsa04145 Pathway Known Explain 0.15621
34 Wall of endosome Component Known Explain 0.15531
35 cytokine-mediated signaling pathway Function Known Explain 0.15026
36 Asthma Disease Known Explain 0.14474
37 HLA-DRB1 gene Gene Inferred Explain 0.11044
38 MYASTHENIA GRAVIS WITH THYMUS HYPERPLASIA Disease Inferred Explain 0.11007
39 Endosomes Component Known Explain 0.09582
40 Dexamethasone Compound Known Explain 0.09266
41 Immune response Function Known Explain 0.06742
42 Myasthenia Gravis, Autoimmune, Experimental Disease Inferred Explain 0.06313
43 BTNL2 gene Gene Inferred Explain 0.06220
44 MYASTHENIA, LIMB-GIRDLE, AUTOIMMUNE Disease Inferred Explain 0.06103
45 Familial infantile myasthenia Disease Inferred Explain 0.05786
46 Neuromuscular Junction Diseases Disease Inferred Explain 0.05671
47 HLA-DOA gene Gene Inferred Explain 0.04574
48 HLA-DQB1 gene Gene Inferred Explain 0.04477
49 HLA-DRA gene Gene Inferred Explain 0.04419
50 HLA-DMA gene Gene Inferred Explain 0.04276
51 HLA-DMB gene Gene Inferred Explain 0.04243
52 HLA-DQA2 gene Gene Inferred Explain 0.04134
53 HLA-DQA1 gene Gene Inferred Explain 0.04096
54 HLA-DOB gene Gene Inferred Explain 0.03824
55 Endoplasmic reticulum, membrane Component Known Explain 0.03695
56 HLA-DPB2 gene Gene Inferred Explain 0.03595
57 Thymus Hyperplasia Disease Inferred Explain 0.03559
58 HLA-DRB4 gene Gene Inferred Explain 0.03515
59 HLA-DRB3 gene Gene Inferred Explain 0.03438
60 Autoimmune Diseases of the Nervous System Disease Inferred Explain 0.03250
61 HLA-DRB5 gene Gene Inferred Explain 0.03191
62 Amiodarone Compound Known Explain 0.03132
63 Metals, Light Compound Inferred Explain 0.02943
64 Golgi Apparatus Component Known Explain 0.02872
65 Endoplasmic Reticulum Component Known Explain 0.02704
66 Hepatitis, Chronic Disease Inferred Explain 0.02527
67 Sarcoidosis, Pulmonary Disease Inferred Explain 0.02523
68 Hepatitis B Disease Inferred Explain 0.02454
69 Metals, Alkaline Earth Compound Inferred Explain 0.02425
70 SARCOIDOSIS, EARLY-ONSET Disease Inferred Explain 0.02399
71 tert-Butylhydroperoxide Compound Known Explain 0.02293
72 Calcium Valproate Compound Known Explain 0.01704
73 Cell membrane Component Known Explain 0.01662
74 Granuloma Disease Inferred Explain 0.01575
75 CD28 gene Gene Inferred Explain 0.01461
76 MHC class II receptor activity Function Inferred Explain 0.01412
77 HLA-DQB2 gene Gene Inferred Explain 0.01328
78 IFNA2 gene Gene Inferred Explain 0.01207
79 integral to membrane Component Known Explain 0.01062
80 Pneumoconiosis Disease Inferred Explain 0.01053
81 Lambert-Eaton Myasthenic Syndrome Disease Inferred Explain 0.01003
82 Lamivudine Compound Inferred Explain 0.00921
83 HP gene Gene Inferred Explain 0.00869
84 Myasthenias Disease Inferred Explain 0.00835
85 MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO Disease Inferred Explain 0.00830
86 Lymphatic Diseases Disease Inferred Explain 0.00763
87 Lymphoproliferative Disorders Disease Inferred Explain 0.00745
88 TNF gene Gene Inferred Explain 0.00727
89 Prednisone Compound Inferred Explain 0.00718
90 ANXA11 gene Gene Inferred Explain 0.00700
91 IL2RA gene Gene Inferred Explain 0.00658
92 Myasthenic Syndromes, Congenital Disease Inferred Explain 0.00653
93 IL18 gene Gene Inferred Explain 0.00617
94 HLA-A gene Gene Inferred Explain 0.00617
95 HLA-F gene Gene Inferred Explain 0.00603
96 CD80 gene Gene Inferred Explain 0.00577
97 HLA-C gene Gene Inferred Explain 0.00545
98 HLA-G gene Gene Inferred Explain 0.00531
99 TGFB1 gene Gene Inferred Explain 0.00523
100 HLA-E gene Gene Inferred Explain 0.00520