|
Metal Ion Binding
Related concepts
|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
zinc ion binding
|
Function
|
Inferred
|
Explain
|
0.08177
|
|
2
|
Protoplasm
|
Component
|
Inferred
|
Explain
|
0.03763
|
|
3
|
Cell Nucleus
|
Component
|
Inferred
|
Explain
|
0.02841
|
|
4
|
DNA Binding
|
Function
|
Inferred
|
Explain
|
0.02608
|
|
5
|
regulation of transcription, DNA-dependent
|
Function
|
Inferred
|
Explain
|
0.01933
|
|
6
|
Transcriptional Regulation
|
Function
|
Inferred
|
Explain
|
0.00999
|
|
7
|
Zinc finger, C2H2-like
|
Domain
|
Inferred
|
Explain
|
0.00722
|
|
8
|
Zinc finger, C2H2-type
|
Domain
|
Inferred
|
Explain
|
0.00707
|
|
9
|
Cyclosporine
|
Compound
|
Inferred
|
Explain
|
0.00643
|
|
10
|
Zinc finger, C2H2-type/integrase, DNA-binding
|
Domain
|
Inferred
|
Explain
|
0.00621
|
|
11
|
Protein Binding
|
Function
|
Inferred
|
Explain
|
0.00568
|
|
12
|
Cytoplasm
|
Component
|
Inferred
|
Explain
|
0.00562
|
|
13
|
Nucleic Acid Binding
|
Function
|
Inferred
|
Explain
|
0.00531
|
|
14
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
|
Compound
|
Inferred
|
Explain
|
0.00467
|
|
15
|
transcription factor activity
|
Function
|
Inferred
|
Explain
|
0.00424
|
|
16
|
hydrolase activity
|
Function
|
Inferred
|
Explain
|
0.00377
|
|
17
|
Benzo(a)pyrene
|
Compound
|
Inferred
|
Explain
|
0.00349
|
|
18
|
IPR013083
|
Domain
|
Inferred
|
Explain
|
0.00338
|
|
19
|
Membrane
|
Component
|
Inferred
|
Explain
|
0.00265
|
|
20
|
Krueppel-associated box
|
Domain
|
Inferred
|
Explain
|
0.00242
|
|
21
|
transcription, DNA-dependent
|
Function
|
Inferred
|
Explain
|
0.00242
|
|
22
|
Tetrachlorodibenzodioxin
|
Compound
|
Inferred
|
Explain
|
0.00230
|
|
23
|
Zinc finger, RING-type
|
Domain
|
Inferred
|
Explain
|
0.00229
|
|
24
|
Vitamin E
|
Compound
|
Inferred
|
Explain
|
0.00222
|
|
25
|
Metallothionein superfamily
|
Domain
|
Known
|
Explain
|
0.00221
|
|
26
|
ligase activity
|
Function
|
Inferred
|
Explain
|
0.00220
|
|
27
|
peptidase activity
|
Function
|
Inferred
|
Explain
|
0.00216
|
|
28
|
Selenium
|
Compound
|
Inferred
|
Explain
|
0.00210
|
|
29
|
integral to membrane
|
Component
|
Inferred
|
Explain
|
0.00207
|
|
30
|
pirinixic acid
|
Compound
|
Inferred
|
Explain
|
0.00199
|
|
31
|
Cytoplasmic matrix
|
Component
|
Inferred
|
Explain
|
0.00190
|
|
32
|
Calcium Valproate
|
Compound
|
Inferred
|
Explain
|
0.00188
|
|
33
|
Metallothionein superfamily, eukaryotic
|
Domain
|
Known
|
Explain
|
0.00185
|
|
34
|
arsenic trioxide
|
Compound
|
Inferred
|
Explain
|
0.00179
|
|
35
|
Aflatoxin B1
|
Compound
|
Inferred
|
Explain
|
0.00177
|
|
36
|
nucleotide binding
|
Function
|
Inferred
|
Explain
|
0.00176
|
|
37
|
Proteolysis
|
Function
|
Inferred
|
Explain
|
0.00164
|
|
38
|
metallopeptidase activity
|
Function
|
Inferred
|
Explain
|
0.00163
|
|
39
|
Estradiol
|
Compound
|
Inferred
|
Explain
|
0.00162
|
|
40
|
Oxidation-Reduction
|
Function
|
Inferred
|
Explain
|
0.00161
|
|
41
|
Zinc finger, FYVE/PHD-type
|
Domain
|
Inferred
|
Explain
|
0.00156
|
|
42
|
Selenite
|
Compound
|
Inferred
|
Explain
|
0.00148
|
|
43
|
transferase activity
|
Function
|
Inferred
|
Explain
|
0.00147
|
|
44
|
Mitochondria
|
Component
|
Inferred
|
Explain
|
0.00147
|
|
45
|
UBE2U gene
|
Gene
|
Inferred
|
Explain
|
0.00141
|
|
46
|
multicellular organismal development
|
Function
|
Inferred
|
Explain
|
0.00135
|
|
47
|
ubiquitin-protein ligase activity
|
Function
|
Inferred
|
Explain
|
0.00134
|
|
48
|
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
Function
|
Inferred
|
Explain
|
0.00132
|
|
49
|
ATP binding
|
Function
|
Inferred
|
Explain
|
0.00131
|
|
50
|
Water
|
Compound
|
Inferred
|
Explain
|
0.00131
|
|
51
|
UBE2D2 gene
|
Gene
|
Inferred
|
Explain
|
0.00124
|
|
52
|
ARF GTPase activator activity
|
Function
|
Inferred
|
Explain
|
0.00123
|
|
53
|
Cell membrane
|
Component
|
Inferred
|
Explain
|
0.00123
|
|
54
|
Adenosine Triphosphate
|
Compound
|
Inferred
|
Explain
|
0.00123
|
|
55
|
metalloendopeptidase activity
|
Function
|
Inferred
|
Explain
|
0.00120
|
|
56
|
Viral life cycle
|
Function
|
Inferred
|
Explain
|
0.00117
|
|
57
|
tert-Butylhydroperoxide
|
Compound
|
Inferred
|
Explain
|
0.00115
|
|
58
|
Zinc finger, PHD-type
|
Domain
|
Inferred
|
Explain
|
0.00115
|
|
59
|
Amiodarone
|
Compound
|
Inferred
|
Explain
|
0.00115
|
|
60
|
regulation of ARF GTPase activity
|
Function
|
Inferred
|
Explain
|
0.00114
|
|
61
|
Calcitriol
|
Compound
|
Inferred
|
Explain
|
0.00113
|
|
62
|
Fluorouracil
|
Compound
|
Inferred
|
Explain
|
0.00108
|
|
63
|
oxidoreductase activity
|
Function
|
Inferred
|
Explain
|
0.00107
|
|
64
|
Zinc finger, C3HC4 RING-type
|
Domain
|
Inferred
|
Explain
|
0.00106
|
|
65
|
Metallothionein, vertebrate
|
Domain
|
Known
|
Explain
|
0.00104
|
|
66
|
UBE2D4 gene
|
Gene
|
Inferred
|
Explain
|
0.00104
|
|
67
|
Nucleoplasm
|
Component
|
Inferred
|
Explain
|
0.00102
|
|
68
|
extracellular region
|
Component
|
Inferred
|
Explain
|
0.00099
|
|
69
|
UBE2D3 gene
|
Gene
|
Inferred
|
Explain
|
0.00099
|
|
70
|
Lipoxygenase, C-terminal
|
Domain
|
Known
|
Explain
|
0.00097
|
|
71
|
UBE2D1 gene
|
Gene
|
Inferred
|
Explain
|
0.00096
|
|
72
|
Manganese/iron superoxide dismutase
|
Domain
|
Known
|
Explain
|
0.00096
|
|
73
|
sequence-specific DNA binding
|
Function
|
Inferred
|
Explain
|
0.00094
|
|
74
|
chromatin modification
|
Function
|
Inferred
|
Explain
|
0.00094
|
|
75
|
Hydralazine
|
Compound
|
Inferred
|
Explain
|
0.00094
|
|
76
|
Adenosine Monophosphate
|
Compound
|
Inferred
|
Explain
|
0.00093
|
|
77
|
Lipoxygenase
|
Domain
|
Known
|
Explain
|
0.00093
|
|
78
|
Zinc finger, CCCH-type
|
Domain
|
Inferred
|
Explain
|
0.00092
|
|
79
|
Physiological Processes
|
Function
|
Inferred
|
Explain
|
0.00092
|
|
80
|
Zinc finger, LIM-type
|
Domain
|
Inferred
|
Explain
|
0.00092
|
|
81
|
Cell Nucleolus
|
Component
|
Inferred
|
Explain
|
0.00091
|
|
82
|
Haemerythrin, iron-binding site
|
Domain
|
Known
|
Explain
|
0.00091
|
|
83
|
RNA Binding
|
Function
|
Inferred
|
Explain
|
0.00091
|
|
84
|
IPR020855
|
Domain
|
Known
|
Explain
|
0.00089
|
|
85
|
Ureohydrolase
|
Domain
|
Known
|
Explain
|
0.00087
|
|
86
|
Diphosphates
|
Compound
|
Inferred
|
Explain
|
0.00087
|
|
87
|
Tretinoin
|
Compound
|
Inferred
|
Explain
|
0.00087
|
|
88
|
Zinc finger, RING-type, conserved site
|
Domain
|
Inferred
|
Explain
|
0.00084
|
|
89
|
Zinc finger, PHD-finger
|
Domain
|
Inferred
|
Explain
|
0.00084
|
|
90
|
TP53 gene
|
Gene
|
Known
|
Explain
|
0.00084
|
|
91
|
Haemerythrin-like, metal-binding
|
Domain
|
Known
|
Explain
|
0.00083
|
|
92
|
GRB2 gene
|
Gene
|
Inferred
|
Explain
|
0.00083
|
|
93
|
IPR020833
|
Domain
|
Known
|
Explain
|
0.00083
|
|
94
|
IPR020834
|
Domain
|
Known
|
Explain
|
0.00083
|
|
95
|
Progesterone
|
Compound
|
Inferred
|
Explain
|
0.00082
|
|
96
|
Ubiquitin
|
Compound
|
Inferred
|
Explain
|
0.00082
|
|
97
|
ZNF446 gene
|
Gene
|
Known
|
Explain
|
0.00082
|
|
98
|
Golgi Apparatus
|
Component
|
Inferred
|
Explain
|
0.00081
|
|
99
|
negative regulation of transcription from RNA polymerase II promoter
|
Function
|
Inferred
|
Explain
|
0.00081
|
|
100
|
IPR020821
|
Domain
|
Known
|
Explain
|
0.00080
|
|