Innate Immune Response

Disease • C1155265

Definition

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_15nov05, GOC:mtg_sensu]

Synonyms

Innate Immune Response • Immune Responses, Innate • Innate Immune Responses • Immune Response, Innate • nonspecific immune response

Linked items?Related concepts, ordered by their global importance in the network.

MAPK1 gene    UBC gene    RELA gene    MAPK3 gene    MAPK14 gene    JUN gene    TRAF6 gene    NFKB1 gene    Immune response    MAPK8 gene    FOS gene    IKBKG gene    IKBKE gene    NFKBIA gene    RPS6KA3 gene    APP gene    PPARG gene    CDK1 gene    MAPK9 gene    MAP2K1 gene   

Related concepts

# Concept name Type Relation Support Score
1 complement activation, classical pathway Function Inferred Explain 0.09996
2 TBKBP1 gene Gene Known Explain 0.08350
3 Complement Activation Function Inferred Explain 0.08098
4 Complement Pathway, Alternative Function Known Explain 0.06944
5 plant-type hypersensitive response Function Known Explain 0.06507
6 Ponericin L Domain Known Explain 0.06386
7 induced systemic resistance Function Known Explain 0.06109
8 melanization defense response Disease Known Explain 0.06085
9 IGLC2 gene Gene Known Explain 0.05388
10 IGLC3 gene Gene Known Explain 0.05388
11 IGLC6 gene Gene Known Explain 0.05388
12 IGLC7 gene Gene Known Explain 0.05388
13 C4B gene Gene Known Explain 0.05232
14 DEFB127 gene Gene Known Explain 0.05218
15 C7 gene Gene Known Explain 0.05105
16 CNPY3 gene Gene Known Explain 0.05070
17 complement activation, lectin pathway Function Known Explain 0.05068
18 CLEC4D gene Gene Known Explain 0.05018
19 CD180 gene Gene Known Explain 0.05008
20 C8A gene Gene Known Explain 0.04962
21 C8B gene Gene Known Explain 0.04927
22 IGKV4-1 gene Gene Known Explain 0.04910
23 DEFB118 gene Gene Known Explain 0.04867
24 natural killer cell mediated immunity Disease Known Explain 0.04838
25 LILRA5 gene Gene Known Explain 0.04744
26 virus induced gene silencing Function Known Explain 0.04625
27 Interleukin-1 receptor, type I/Toll precursor Domain Known Explain 0.04513
28 CLEC10A gene Gene Known Explain 0.04492
29 IGKV1-5 gene Gene Known Explain 0.04484
30 hemolymph coagulation Function Known Explain 0.04477
31 defense response, incompatible interaction Function Known Explain 0.04472
32 GZMM gene Gene Known Explain 0.04186
33 C2 gene Gene Known Explain 0.04175
34 CLEC4A gene Gene Known Explain 0.04104
35 CLEC6A gene Gene Known Explain 0.04048
36 CFP gene Gene Known Explain 0.04025
37 LY86 gene Gene Known Explain 0.04007
38 IL1RL2 gene Gene Known Explain 0.03987
39 TREML1 gene Gene Known Explain 0.03950
40 C4BPA gene Gene Known Explain 0.03945
41 CLEC4C gene Gene Known Explain 0.03870
42 IGLC1 gene Gene Known Explain 0.03851
43 NLRX1 gene Gene Known Explain 0.03789
44 C9 gene Gene Known Explain 0.03750
45 CR1 gene Gene Known Explain 0.03736
46 MASP2 gene Gene Known Explain 0.03718
47 Toll-Interleukin receptor Domain Known Explain 0.03641
48 innate immune response in mucosa Function Known Explain 0.03628
49 SARM1 gene Gene Known Explain 0.03617
50 C8G gene Gene Known Explain 0.03605
51 CRISP3 gene Gene Known Explain 0.03584
52 IL18RAP gene Gene Known Explain 0.03466
53 RNASE7 gene Gene Known Explain 0.03437
54 PLUNC gene Gene Known Explain 0.03379
55 C4BPB gene Gene Known Explain 0.03329
56 IL1RAPL2 gene Gene Known Explain 0.03317
57 C5 gene Gene Known Explain 0.03283
58 C1QC gene Gene Known Explain 0.03210
59 TICAM2 gene Gene Known Explain 0.03136
60 C4A gene Gene Known Explain 0.03121
61 AKIRIN2 gene Gene Known Explain 0.03067
62 PELI2 gene Gene Known Explain 0.03066
63 C1RL gene Gene Known Explain 0.03056
64 MASP1 gene Gene Known Explain 0.03039
65 C1QB gene Gene Known Explain 0.02965
66 C1R gene Gene Known Explain 0.02957
67 CFI gene Gene Known Explain 0.02955
68 MARCO gene Gene Known Explain 0.02933
69 POLR3E gene Gene Known Explain 0.02915
70 PYDC1 gene Gene Known Explain 0.02886
71 CFB gene Gene Known Explain 0.02884
72 CFD gene Gene Known Explain 0.02864
73 UNC93B1 gene Gene Known Explain 0.02862
74 C1S gene Gene Known Explain 0.02856
75 C3 gene Gene Known Explain 0.02849
76 S100A12 gene Gene Known Explain 0.02827
77 DHX58 gene Gene Known Explain 0.02827
78 SIGIRR gene Gene Known Explain 0.02780
79 PGLYRP4 gene Gene Known Explain 0.02777
80 C6 gene Gene Known Explain 0.02766
81 PGLYRP3 gene Gene Known Explain 0.02766
82 TLR10 gene Gene Known Explain 0.02765
83 C1QA gene Gene Known Explain 0.02728
84 IFITM3 gene Gene Known Explain 0.02649
85 APOBEC3F gene Gene Known Explain 0.02641
86 CR2 gene Gene Known Explain 0.02640
87 SPON2 gene Gene Known Explain 0.02640
88 DEFB1 gene Gene Known Explain 0.02635
89 IL18R1 gene Gene Known Explain 0.02603
90 TAB3 gene Gene Known Explain 0.02545
91 CRCP gene Gene Known Explain 0.02527
92 PGLYRP1 gene Gene Known Explain 0.02516
93 IL27 gene Gene Known Explain 0.02493
94 CD55 gene Gene Known Explain 0.02471
95 TLR1 gene Gene Known Explain 0.02464
96 IL1RAPL1 gene Gene Known Explain 0.02431
97 CAPZA2 gene Gene Known Explain 0.02408
98 NLRC5 gene Gene Known Explain 0.02389
99 IRGM gene Gene Known Explain 0.02385
100 DUSP7 gene Gene Known Explain 0.02329