|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
integral to membrane
|
Component
|
Inferred
|
Explain
|
0.10177
|
|
2
|
Cyclosporine
|
Compound
|
Inferred
|
Explain
|
0.00810
|
|
3
|
Biological Transport
|
Function
|
Inferred
|
Explain
|
0.00680
|
|
4
|
Endoplasmic Reticulum
|
Component
|
Inferred
|
Explain
|
0.00598
|
|
5
|
Endoplasmic reticulum, membrane
|
Component
|
Inferred
|
Explain
|
0.00566
|
|
6
|
Golgi Apparatus
|
Component
|
Inferred
|
Explain
|
0.00541
|
|
7
|
Ion Transport
|
Function
|
Inferred
|
Explain
|
0.00507
|
|
8
|
Transmembrane Transport
|
Function
|
Inferred
|
Explain
|
0.00503
|
|
9
|
Golgi membrane
|
Component
|
Inferred
|
Explain
|
0.00479
|
|
10
|
potassium ion transport
|
Function
|
Inferred
|
Explain
|
0.00418
|
|
11
|
Protein Binding
|
Function
|
Inferred
|
Explain
|
0.00417
|
|
12
|
Benzo(a)pyrene
|
Compound
|
Inferred
|
Explain
|
0.00401
|
|
13
|
Mitochondria
|
Component
|
Inferred
|
Explain
|
0.00355
|
|
14
|
receptor activity
|
Function
|
Inferred
|
Explain
|
0.00345
|
|
15
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
|
Compound
|
Inferred
|
Explain
|
0.00343
|
|
16
|
transporter activity
|
Function
|
Inferred
|
Explain
|
0.00339
|
|
17
|
Tetrachlorodibenzodioxin
|
Compound
|
Inferred
|
Explain
|
0.00325
|
|
18
|
Cytoplasm
|
Component
|
Inferred
|
Explain
|
0.00312
|
|
19
|
integral to plasma membrane
|
Component
|
Inferred
|
Explain
|
0.00299
|
|
20
|
Cell membrane
|
Component
|
Known
|
Explain
|
0.00264
|
|
21
|
Calcium Valproate
|
Compound
|
Inferred
|
Explain
|
0.00258
|
|
22
|
pirinixic acid
|
Compound
|
Inferred
|
Explain
|
0.00249
|
|
23
|
Inner mitochondrial membrane
|
Component
|
Inferred
|
Explain
|
0.00248
|
|
24
|
protein transport
|
Function
|
Inferred
|
Explain
|
0.00244
|
|
25
|
Metal Ion Binding
|
Function
|
Inferred
|
Explain
|
0.00228
|
|
26
|
Aflatoxin B1
|
Compound
|
Inferred
|
Explain
|
0.00224
|
|
27
|
molecular_function
|
Function
|
Inferred
|
Explain
|
0.00219
|
|
28
|
Physiological Processes
|
Function
|
Inferred
|
Explain
|
0.00216
|
|
29
|
Estradiol
|
Compound
|
Inferred
|
Explain
|
0.00208
|
|
30
|
Selenite
|
Compound
|
Inferred
|
Explain
|
0.00201
|
|
31
|
Cell Nucleus
|
Component
|
Inferred
|
Explain
|
0.00181
|
|
32
|
Selenium
|
Compound
|
Inferred
|
Explain
|
0.00173
|
|
33
|
ATP binding
|
Function
|
Inferred
|
Explain
|
0.00172
|
|
34
|
glycosyltransferase activity
|
Function
|
Inferred
|
Explain
|
0.00168
|
|
35
|
arsenic trioxide
|
Compound
|
Inferred
|
Explain
|
0.00158
|
|
36
|
voltage-gated potassium channel activity
|
Function
|
Inferred
|
Explain
|
0.00153
|
|
37
|
transferase activity
|
Function
|
Inferred
|
Explain
|
0.00151
|
|
38
|
Vitamin E
|
Compound
|
Inferred
|
Explain
|
0.00148
|
|
39
|
Signal Transduction
|
Function
|
Inferred
|
Explain
|
0.00146
|
|
40
|
Binding (Molecular Function)
|
Function
|
Inferred
|
Explain
|
0.00145
|
|
41
|
ion channel activity
|
Function
|
Inferred
|
Explain
|
0.00142
|
|
42
|
nucleotide binding
|
Function
|
Inferred
|
Explain
|
0.00134
|
|
43
|
voltage-gated ion channel activity
|
Function
|
Inferred
|
Explain
|
0.00133
|
|
44
|
tert-Butylhydroperoxide
|
Compound
|
Inferred
|
Explain
|
0.00133
|
|
45
|
Cell Adhesion
|
Function
|
Inferred
|
Explain
|
0.00133
|
|
46
|
sodium ion transport
|
Function
|
Inferred
|
Explain
|
0.00130
|
|
47
|
sugar binding
|
Function
|
Inferred
|
Explain
|
0.00127
|
|
48
|
Potassium channel, inwardly rectifying, Kir, conserved region 2
|
Domain
|
Inferred
|
Explain
|
0.00126
|
|
49
|
voltage-gated potassium channel complex
|
Component
|
Inferred
|
Explain
|
0.00126
|
|
50
|
Endosomes
|
Component
|
Inferred
|
Explain
|
0.00125
|
|
51
|
Potassium channel, inwardly rectifying, Kir, cytoplasmic
|
Domain
|
Inferred
|
Explain
|
0.00124
|
|
52
|
cellular_component
|
Component
|
Inferred
|
Explain
|
0.00122
|
|
53
|
Immunoglobulin-like fold
|
Domain
|
Inferred
|
Explain
|
0.00121
|
|
54
|
vesicle-mediated transport
|
Function
|
Inferred
|
Explain
|
0.00121
|
|
55
|
Calcitriol
|
Compound
|
Inferred
|
Explain
|
0.00120
|
|
56
|
Potassium channel, inwardly rectifying, Kir
|
Domain
|
Inferred
|
Explain
|
0.00119
|
|
57
|
Muscarinic acetylcholine receptor
|
Domain
|
Known
|
Explain
|
0.00118
|
|
58
|
Chloride channel, voltage gated
|
Domain
|
Known
|
Explain
|
0.00117
|
|
59
|
Sodium:neurotransmitter symporter
|
Domain
|
Known
|
Explain
|
0.00117
|
|
60
|
membrane fraction
|
Component
|
Inferred
|
Explain
|
0.00116
|
|
61
|
extracellular region
|
Component
|
Inferred
|
Explain
|
0.00116
|
|
62
|
GPCR, family 2, secretin-like, conserved site
|
Domain
|
Known
|
Explain
|
0.00115
|
|
63
|
zinc ion binding
|
Function
|
Inferred
|
Explain
|
0.00114
|
|
64
|
Ion transport
|
Domain
|
Known
|
Explain
|
0.00113
|
|
65
|
Wall of lysosome
|
Component
|
Inferred
|
Explain
|
0.00111
|
|
66
|
Hydralazine
|
Compound
|
Inferred
|
Explain
|
0.00111
|
|
67
|
Fluorouracil
|
Compound
|
Inferred
|
Explain
|
0.00108
|
|
68
|
hydrolase activity
|
Function
|
Inferred
|
Explain
|
0.00107
|
|
69
|
Cytoplasmic Vesicles
|
Component
|
Inferred
|
Explain
|
0.00107
|
|
70
|
Cytoplasmic matrix
|
Component
|
Inferred
|
Explain
|
0.00107
|
|
71
|
calcium ion binding
|
Function
|
Inferred
|
Explain
|
0.00100
|
|
72
|
ABC transporter-like
|
Domain
|
Inferred
|
Explain
|
0.00100
|
|
73
|
Response to stimulus physiology
|
Function
|
Inferred
|
Explain
|
0.00100
|
|
74
|
Voltage-dependent calcium channel, gamma subunit
|
Domain
|
Known
|
Explain
|
0.00097
|
|
75
|
intracellular protein transport
|
Function
|
Inferred
|
Explain
|
0.00097
|
|
76
|
Sugar transporter, conserved site
|
Domain
|
Known
|
Explain
|
0.00096
|
|
77
|
protein amino acid glycosylation
|
Function
|
Inferred
|
Explain
|
0.00096
|
|
78
|
Immunoglobulin-like
|
Domain
|
Inferred
|
Explain
|
0.00094
|
|
79
|
potassium channel activity
|
Function
|
Inferred
|
Explain
|
0.00094
|
|
80
|
Mechanosensitive ion channel MscS
|
Domain
|
Known
|
Explain
|
0.00094
|
|
81
|
Major facilitator superfamily, general substrate transporter
|
Domain
|
Inferred
|
Explain
|
0.00093
|
|
82
|
Proteolysis
|
Function
|
Inferred
|
Explain
|
0.00093
|
|
83
|
GPCR, family 2, extracellular region
|
Domain
|
Known
|
Explain
|
0.00092
|
|
84
|
Uridine Diphosphate
|
Compound
|
Inferred
|
Explain
|
0.00085
|
|
85
|
Yip1 domain
|
Domain
|
Known
|
Explain
|
0.00082
|
|
86
|
Wall of Golgi cistern
|
Component
|
Inferred
|
Explain
|
0.00082
|
|
87
|
PMP-22/EMP/MP20
|
Domain
|
Known
|
Explain
|
0.00082
|
|
88
|
Anion exchange, conserved site
|
Domain
|
Known
|
Explain
|
0.00081
|
|
89
|
Anion exchange protein
|
Domain
|
Known
|
Explain
|
0.00081
|
|
90
|
Protein Processing, Post-Translational
|
Function
|
Inferred
|
Explain
|
0.00081
|
|
91
|
voltage-gated chloride channel activity
|
Function
|
Inferred
|
Explain
|
0.00081
|
|
92
|
Microsomes
|
Component
|
Inferred
|
Explain
|
0.00079
|
|
93
|
Water
|
Compound
|
Inferred
|
Explain
|
0.00079
|
|
94
|
respiratory electron transport chain process
|
Function
|
Inferred
|
Explain
|
0.00078
|
|
95
|
Chloride channel, core
|
Domain
|
Inferred
|
Explain
|
0.00078
|
|
96
|
Amiodarone
|
Compound
|
Inferred
|
Explain
|
0.00078
|
|
97
|
Immune response
|
Function
|
Inferred
|
Explain
|
0.00078
|
|
98
|
neurotransmitter transport
|
Function
|
Inferred
|
Explain
|
0.00078
|
|
99
|
ABC transporter, conserved site
|
Domain
|
Inferred
|
Explain
|
0.00078
|
|
100
|
calcium ion transport
|
Function
|
Inferred
|
Explain
|
0.00075
|