Apoptosis

Function • C0162638

Definition

(ap-o-TOE-sis) A normal series of events in a cell that leads to its death.

Synonyms

Apoptosis • Programmed Cell Death • Programmed Cell Death, Type I • type I programmed cell death • Apoptosis Pathway • programmed cell death by apoptosis • apoptotic programmed cell death • PCD • apoptotic cell death

Linked items?Related concepts, ordered by their global importance in the network.

TP53 gene    Apoptosis    Apoptosis    UBC gene    TNF gene    BCL2 gene    RELA gene    CASP3 gene    SH3GLB1 gene    AKT1 gene    Cell Cycle    TRAF6 gene    CTNNB1 gene    EP300 gene    NFKB1 gene    MAPK8 gene    IL1B gene    PIK3R1 gene    IKBKG gene    Pathways in cancer - Homo sapiens (human)   

Related concepts

# Concept name Type Relation Support Score
1 myeloid cell apoptosis Function Known Explain 0.00841
2 virus-infected cell apoptosis Function Known Explain 0.00788
3 Protein Binding Function Inferred Explain 0.00782
4 glial cell apoptosis Function Known Explain 0.00778
5 DAPL1 gene Gene Known Explain 0.00772
6 inflammatory cell apoptosis Function Known Explain 0.00756
7 host programmed cell death induced by symbiont Function Known Explain 0.00756
8 Caspase-activated nuclease CIDE-N Domain Known Explain 0.00749
9 BCL2L15 gene Gene Known Explain 0.00747
10 BLID gene Gene Known Explain 0.00726
11 SHF gene Gene Known Explain 0.00722
12 Anoikis Function Known Explain 0.00703
13 Ribosomal protein S29, mitochondrial Domain Known Explain 0.00701
14 TMEM85 gene Gene Known Explain 0.00699
15 NAIF1 gene Gene Known Explain 0.00693
16 nurse cell apoptosis Function Known Explain 0.00685
17 Cell Nucleus Component Inferred Explain 0.00684
18 FAST kinase leucine-rich Domain Known Explain 0.00681
19 SPIN2B gene Gene Known Explain 0.00676
20 SPATA3 gene Gene Known Explain 0.00663
21 FAM188A gene Gene Known Explain 0.00663
22 Cytoplasm Component Inferred Explain 0.00661
23 transformed cell apoptosis Function Known Explain 0.00656
24 TCTN3 gene Gene Known Explain 0.00655
25 LGALS12 gene Gene Known Explain 0.00653
26 Apoptosis regulator Bcl-2 protein, BAG Domain Known Explain 0.00651
27 C16orf5 gene Gene Known Explain 0.00636
28 NB-ARC Domain Known Explain 0.00634
29 SPATA4 gene Gene Known Explain 0.00627
30 Programmed Cell Death, Type II Function Known Explain 0.00625
31 ovarian follicle atresia Function Known Explain 0.00623
32 CASP12 gene Gene Known Explain 0.00603
33 FAM3B gene Gene Known Explain 0.00596
34 USP17L3 gene Gene Known Explain 0.00593
35 USP17L5 gene Gene Known Explain 0.00593
36 GZMH gene Gene Known Explain 0.00574
37 USP17L1P gene Gene Known Explain 0.00565
38 PDCL3 gene Gene Known Explain 0.00562
39 Caspase-6 Domain Known Explain 0.00558
40 Peptidase C14, caspase precursor p45, core Domain Known Explain 0.00558
41 Caspase-7 Domain Known Explain 0.00557
42 Caspase-3-related Domain Known Explain 0.00550
43 DRAM1 gene Gene Known Explain 0.00549
44 Fas receptor Domain Known Explain 0.00547
45 DNAJB13 gene Gene Known Explain 0.00545
46 FASTKD1 gene Gene Known Explain 0.00541
47 PNMA3 gene Gene Known Explain 0.00537
48 FASTKD3 gene Gene Known Explain 0.00535
49 ENDOD1 gene Gene Known Explain 0.00534
50 TRIM69 gene Gene Known Explain 0.00528
51 Induction of Apoptosis Function Inferred Explain 0.00526
52 apoptosis in response to endoplasmic reticulum stress Function Known Explain 0.00522
53 Fas ligand Domain Known Explain 0.00519
54 GSDMA gene Gene Known Explain 0.00517
55 TM2D1 gene Gene Known Explain 0.00516
56 CIDEC gene Gene Known Explain 0.00516
57 GRAMD4 gene Gene Known Explain 0.00515
58 BCL2L12 gene Gene Known Explain 0.00509
59 ARHGEF17 gene Gene Known Explain 0.00506
60 GZMM gene Gene Known Explain 0.00503
61 PPP1R13L gene Gene Known Explain 0.00501
62 apoptosis involved in morphogenesis Function Known Explain 0.00496
63 PLEKHG2 gene Gene Known Explain 0.00493
64 CIDEB gene Gene Known Explain 0.00491
65 DRAM2 gene Gene Known Explain 0.00490
66 GML gene Gene Known Explain 0.00489
67 GPR109A gene Gene Known Explain 0.00487
68 TP53AIP1 gene Gene Known Explain 0.00487
69 BLCAP gene Gene Known Explain 0.00485
70 FASTKD5 gene Gene Known Explain 0.00483
71 PPP3R2 gene Gene Known Explain 0.00482
72 developmental programmed cell death Function Known Explain 0.00479
73 TNS4 gene Gene Known Explain 0.00478
74 TBRG4 gene Gene Known Explain 0.00477
75 ZNF346 gene Gene Known Explain 0.00470
76 MAGEH1 gene Gene Known Explain 0.00469
77 TNFRSF6B gene Gene Known Explain 0.00469
78 MRPS30 gene Gene Known Explain 0.00467
79 Zinc finger, hepatitis C virus non-structural 5a-type Domain Known Explain 0.00463
80 ZDHHC16 gene Gene Known Explain 0.00460
81 SLTM gene Gene Known Explain 0.00457
82 CD5L gene Gene Known Explain 0.00456
83 FAM176A gene Gene Known Explain 0.00455
84 PACS2 gene Gene Known Explain 0.00449
85 TIAF1 gene Gene Known Explain 0.00449
86 RFFL gene Gene Known Explain 0.00446
87 CSRNP2 gene Gene Known Explain 0.00446
88 BCL7C gene Gene Known Explain 0.00445
89 CLPTM1L gene Gene Known Explain 0.00443
90 induction of apoptosis by extracellular signals Function Inferred Explain 0.00443
91 ELMO3 gene Gene Known Explain 0.00432
92 TNFRSF18 gene Gene Known Explain 0.00432
93 EAF2 gene Gene Known Explain 0.00428
94 PSMB7 gene Gene Known Explain 0.00426
95 Cyclosporine Compound Inferred Explain 0.00424
96 Hepatitis C virus non-structural 5a, region 1b Domain Known Explain 0.00421
97 HINT2 gene Gene Known Explain 0.00419
98 CGB5 gene Gene Known Explain 0.00418
99 FASTKD2 gene Gene Known Explain 0.00416
100 PERP gene Gene Known Explain 0.00416