Benzo(a)pyrene

Compound • C0005052

Definition

A crystalline, aromatic hydrocarbon consisting of five fused benzene rings and formed during the incomplete combustion of organic matter. 3,4-Benzpyrene is primarily found in gasoline and diesel exhaust, cigarette smoke, coal tar and coal tar pitch, charc

Synonyms

Benzo(a)pyrene • Benzo[a]pyrene • 3,4-Benzopyrene • 3,4 Benzopyrene • 3,4-Benzpyrene • 3,4 Benzpyrene • Benzo[d,e,f]chrysene • BENZOPYRENE AA 0304 • BENZOPYRENE A • Benzo(a)pyrene [Chemical/Ingredient]

Linked items?Related concepts, ordered by their global importance in the network.

ESR1 gene    TP53 gene    MAPK1 gene    UVRAG gene    GABARAPL1 gene    MYC gene    TNF gene    EGFR gene    BCL2 gene    CYP3A4 gene    RELA gene    CASP3 gene    MAPK3 gene    AKT1 gene    MAPK14 gene    AR gene    JUN gene    CYP1A1 gene    ULK2 gene    CYP1A2 gene   

Related concepts

# Concept name Type Relation Support Score
1 Cyclosporine Compound Inferred Explain 0.01347
2 Aflatoxin B1 Compound Inferred Explain 0.01051
3 Tetrachlorodibenzodioxin Compound Inferred Explain 0.00912
4 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Compound Inferred Explain 0.00807
5 Cytoplasm Component Inferred Explain 0.00650
6 Protein Binding Function Inferred Explain 0.00646
7 Cell Nucleus Component Inferred Explain 0.00636
8 Estradiol Compound Inferred Explain 0.00522
9 Membrane Component Inferred Explain 0.00457
10 integral to membrane Component Inferred Explain 0.00449
11 Metal Ion Binding Function Inferred Explain 0.00350
12 Cell membrane Component Inferred Explain 0.00325
13 pirinixic acid Compound Inferred Explain 0.00293
14 arsenic trioxide Compound Inferred Explain 0.00265
15 Calcium Valproate Compound Inferred Explain 0.00261
16 Cytoplasmic matrix Component Inferred Explain 0.00251
17 Protoplasm Component Inferred Explain 0.00243
18 nucleotide binding Function Inferred Explain 0.00238
19 Fluorouracil Compound Inferred Explain 0.00230
20 zinc ion binding Function Inferred Explain 0.00229
21 tert-Butylhydroperoxide Compound Inferred Explain 0.00223
22 Selenium Compound Inferred Explain 0.00222
23 Calcitriol Compound Inferred Explain 0.00222
24 Vitamin E Compound Inferred Explain 0.00220
25 extracellular region Component Inferred Explain 0.00212
26 DNA Binding Function Inferred Explain 0.00167
27 Tretinoin Compound Inferred Explain 0.00163
28 Selenite Compound Inferred Explain 0.00163
29 bisphenol A Compound Inferred Explain 0.00157
30 Signal Transduction Function Inferred Explain 0.00154
31 Mitochondria Component Inferred Explain 0.00153
32 Progesterone Compound Inferred Explain 0.00153
33 ATP binding Function Inferred Explain 0.00141
34 Endoplasmic Reticulum Component Inferred Explain 0.00130
35 Golgi Apparatus Component Inferred Explain 0.00127
36 Genistein Compound Inferred Explain 0.00127
37 Cytoskeleton Component Inferred Explain 0.00123
38 decitabine Compound Inferred Explain 0.00122
39 integral to plasma membrane Component Inferred Explain 0.00113
40 sodium arsenite Compound Inferred Explain 0.00110
41 GRB2 gene Gene Inferred Explain 0.00109
42 hydrolase activity Function Inferred Explain 0.00107
43 molecular_function Function Inferred Explain 0.00104
44 Doxorubicin Compound Inferred Explain 0.00103
45 Asbestos, Crocidolite Compound Inferred Explain 0.00103
46 7-ethyl-10-hydroxycamptothecin Compound Inferred Explain 0.00102
47 multicellular organismal development Function Inferred Explain 0.00102
48 regulation of transcription, DNA-dependent Function Inferred Explain 0.00100
49 Binding (Molecular Function) Function Inferred Explain 0.00099
50 Hydralazine Compound Inferred Explain 0.00099
51 Adenosine Triphosphate Compound Inferred Explain 0.00096
52 Amiodarone Compound Inferred Explain 0.00095
53 resveratrol Compound Inferred Explain 0.00095
54 Nucleoplasm Component Inferred Explain 0.00094
55 testosterone enanthate Compound Inferred Explain 0.00093
56 Transcriptional Regulation Function Inferred Explain 0.00092
57 transcription factor activity Function Inferred Explain 0.00092
58 Arsenic Compound Inferred Explain 0.00092
59 Apoptosis Function Inferred Explain 0.00090
60 transferase activity Function Inferred Explain 0.00090
61 TP53 gene Gene Known Explain 0.00088
62 Physiological Processes Function Inferred Explain 0.00088
63 MYC gene Gene Known Explain 0.00087
64 receptor activity Function Inferred Explain 0.00085
65 Extracellular Space Other Inferred Explain 0.00084
66 cellular_component Component Inferred Explain 0.00081
67 Transmembrane Transport Function Inferred Explain 0.00080
68 GABARAPL1 gene Gene Known Explain 0.00078
69 Water Compound Inferred Explain 0.00077
70 Tamoxifen Compound Inferred Explain 0.00076
71 EGFR gene Gene Known Explain 0.00076
72 ESR1 gene Gene Known Explain 0.00076
73 MAPK14 gene Gene Known Explain 0.00075
74 Endoplasmic reticulum, membrane Component Inferred Explain 0.00075
75 Cell Cycle Function Inferred Explain 0.00074
76 UVRAG gene Gene Known Explain 0.00074
77 calcium ion binding Function Inferred Explain 0.00073
78 Intercellular Junctions Other Inferred Explain 0.00071
79 UBC gene Gene Inferred Explain 0.00071
80 YWHAG gene Gene Inferred Explain 0.00070
81 CDK2 gene Gene Known Explain 0.00070
82 Adenosine Diphosphate Compound Inferred Explain 0.00070
83 Raloxifene Compound Inferred Explain 0.00068
84 HAVCR2 gene Gene Known Explain 0.00068
85 YWHAZ gene Gene Inferred Explain 0.00066
86 Quercetin Compound Inferred Explain 0.00066
87 Prostatic Neoplasms Disease Known Explain 0.00065
88 Systemic lupus erythematosus - Homo sapiens (human) Pathway Inferred Explain 0.00064
89 MAPK1 gene Gene Known Explain 0.00064
90 GABARAP gene Gene Inferred Explain 0.00064
91 JUN gene Gene Known Explain 0.00063
92 ULK2 gene Gene Known Explain 0.00063
93 Cell Differentiation process Function Inferred Explain 0.00062
94 methylselenic acid Compound Inferred Explain 0.00062
95 Benzopyrenes Compound Known Explain 0.00062
96 small GTPase mediated signal transduction Function Inferred Explain 0.00060
97 Blood coagulation Function Inferred Explain 0.00060
98 RELA gene Gene Known Explain 0.00060
99 protein transport Function Inferred Explain 0.00060
100 Etoposide Compound Inferred Explain 0.00059